| Drug Name | Active Ingred | Mfr | Indication | Approval Date |
AHFS Class | NDA Sub Type* |
Appl No |
|---|---|---|---|---|---|---|---|
| Lutathera® | lutetium Lu-177 dotatate | Advanced Accelerator Applications | somatostatin receptor-positive gastroenteropancreatic neuroendocrine tumors (GEP-NETs) | 2018/01/26 | 10:00 - Antineoplastic Agents; 78:00 - Radioactive Agents | 1P | 208700 |
| Firvanq® | vancomoycin | RxM Therapeutics | C. diff-associated diarrhea, enterocolitis (S. aureus [incl MRSA]) | 2018/01/26 | 8:12.28.16 - Glycopeptides | 5P | 208910 |
| Symfi Lo® | efavirenz; lamivudine; tenofovir disoproxil | Mylan | HIV-1 infection | 2018/02/05 | 8:18.08.16 - HIV Nonnucleoside Reverse Transcriptase Inhibitors; 8:18.08.20 HIV Nucleoside and Nucleotide Reverse Transcriptase Inhibitors | 3P | 208255 |
| Biktarvy® | bictegravir; emtracitabine; tenofovir alafenamide | Gilead | HIV-1 infection | 2018/02/07 | 8:18.08.12 - HIV Integrase Inhibitors; 8:18.08.20 HIV Nucleoside and Nucleotide Reverse Transcriptase Inhibitors | 1/4P | 210251 |
| Symdeko® | tezacaftor; ivacaftor | Vertex | cystic fibrosis (CF) with mutation of CFTR gene | 2018/02/12 | 48:14.04 - Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) Correctors; 48:14.12 - Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) Potentiators | 1P | 210491 |
| Erleada® | apalutamide | Janssen | non-metastatic castration-resistant prostate cancer | 2018/02/14 | 10:00 - Antineoplastic Agents | 1P | 210951 |
| Osmolex ER® | amantadine | Osmotica Pharm | Parkinsons; drug-induced extrapyramidal reactions | 2018/02/16 | 28:36.04 - Adamantanes | 3S | 209410 |
| Lusduna® | insulin glargine | Merck Sharp Dohme | diabetes | 2018/02/22 | 68:20.08 - Insulins | 5S | 209764 |
| Apadaz® | benzhydrocodone; acetaminophen | KemPharm | acute severe pain | 2018/02/23 | 28:08.08 - Opiate Agonists; 28:08.92 - Analgesics and Antipyretics, Misc | 4S | 208653 |
| Cimduo® | lamivudine; tenofovir disoproxil fumerate | Matrix | HIV-1 infection | 2018/02/28 | 8:18.08.20 - HIV Nucleoside and Nucleotide Reverse Transcriptase Inhibitors (NNRTI) | 4P | 022141 |
| ZTLido® | lidocaine | Scilex | pain associated with post-herpetic neuralgia (PHN) | 2018/02/28 | 72:00 - Local Anesthetics | 5S | 207962 |
| Trogarzo® | ibalizumab-uiyk | Taimed | HIV-1 infection with multidrug resistance | 2018/03/06 | 8:18.08.04 - HIV Entry and Fusion Inhibitors | 761065 | |
| Ilumya® | tildrakizumab-asmn | MSD / Sun Pharma | plaque psoriasis | 2018/03/20 | 84:92 - Skin and Mucous Membrane Agents, Misc | 761067 | |
| Symfi® | efavirenz; lamivudine; tenofovir disoproxil | Matrix | HIV-1 infection | 2018/03/22 | 8:18.08.16 - HIV Nonnucleoside Reverse Transcriptase Inhibitors; 8:18.08.20 HIV Nucleoside and Nucleotide Reverse Transcriptase Inhibitors | 4 | 022142 |
| Zumandimine® | drospirenone; ethinyl estradiol | Aurobindo | birth control | 2018/03/26 | 68:12 - Contraceptives | 209407 | |
| Tavalisse® | fostamatinib | Rigel | chronic immune thrombocytopenia (ITP) | 2018/04/17 | 20:92 - Blood Formation, Coagulation, and Thrombosis Agents; Misc | 1S | 209299 |
| Crysvita® | burosumab-twza | Ultragenyx | X-linked hypophosphatemia (a vitamin D-resistant form of rickets) | 2018/04/17 | 40:92 - Electrolytic, Caloric, and Water Balance Agents; Misc | 761068 | |
| Akynzeo® for Injection | fosnetupitant; palonosetron | Helsinn | acute and delayed nausea and vomiting associated with initial and repeat courses of highly emetogenic cancer chemotherapy | 2018/04/19 | 56:22.32 - Neurokinin-1 Receptor Antagonists; 56:22.20 - 5-HT3 Receptor Antagonists | 1S | 210493 |
| Jynarque® | tolvaptan | Otsuka | autosomal dominant polycystic kidney disease (ADPKD) | 2018/04/23 | 40:28.28 - Vasopressin Antagonists | 10P | 204441 |
| Andexxa® | factor Xa (recombinant), inactivated-zhzo | Portola | reversal of anticoagulation is needed due to life-threatening or uncontrolled bleeding | 2018/05/03 | 20:28.92 - Antihemorrhagic Agents, Misc | 125586 | |
| Plenvu® | PEG 3350; sod ascorbate; sod sulfate; ascorbic acid; sod chloride; pot chloride | Northstar | colon preparation for colonoscopy | 2018/05/04 | 56:12 - Cathartics and Laxatives | 2S | 209381 |
| Retacrit® | epoetin alfa-epbx | Hospira | anemia | 2018/05/15 | 20:16 - Hematopoietic Agents | 125545 | |
| Lucemyra® | lofexidine | US Worldmeds | mitigation of opioid withdrawal symptoms | 2018/05/16 | 12:12.04 - alpha-Adrenergic Agonists | 1P | 209229 |
| Aimovig® | erenumab-aooe | Amgen | migraine headaches | 2018/05/17 | 28:32.92 - Antimigraine Agents, Misc | 761077 | |
| Lokelma® | sodium zirconium cyclosilicate | AstraZeneca | hyperkalemia | 2018/05/18 | 40:18.18 - Potassium-removing Agents | 1S | 207078 |
| Doptelet® | avatrombopag | Akarx | thrombocytopenia | 2018/05/21 | 20:16 - Hematopoietic Agents | 1P | 210238 |
| Yonsa® | abiraterone | Sun Pharma | metastatic castration-resistant prostate cancer (CRPC) | 2018/05/22 | 10:00 - Antineoplastic Agents | 5S | 210308 |
| Palynziq® | pegvaliase-pqpz | Biomarin | hyperphenylalaninaemia in patients with phenylketonuria (PKU) | 2018/05/24 | 44:00 - Enzymes | 761079 | |
| Imvexxy® | estradiol | Therapeutics MD | moderate to severe dyspareunia due to menopause | 2018/05/29 | 68:16.04 - Estrogens | 5S | 208564 |
| Olumiant® | baricitinib | Eli Lilly | moderate to severe rheumatoid arthritis | 2018/05/31 | 92:36 - Disease-modifying Antirheumatic Drugs (DMARD) | 1S | 207924 |
| Consensi® | amlodipine; celecoxib | Kitov | combination therapy for hypertension and osteoarthritis | 2018/05/31 | 24:28.08 - Dihydropyridines; 28:08.04.08 - Cyclooxygenase-2 (COX-2) Inhibitors | 4S | 210045 |
| Fulphila® | pegfilgrastim-jmdb | Mylan | febrile neutropenia | 2018/06/04 | 20:16 - Hematopoietic Agents | 761075 | |
| moxidectin | moxidectin | Medicines Development | onchocerciasis | 2018/06/13 | 8:08 - Anthelmintics | 1P/O | 210867 |
| Lymepak® | doxycycline hyclate | Chartwell | early Lyme disease | 2018/06/15 | 8:12.24 - Tetracyclines | 5S | 209844 |
| Nocdurna® | desmopressin | Ferring | nocturia due to nocturnal polyuria | 2018/06/21 | 68:28 - Pituitary | 5S | 022517 |
| Ablysinol® | dehydrated alcohol | Belcher | alcohol septal ablation | 2018/06/21 | 24:16 - Sclerosing Agents | 5S | 207987 |
| Zemdri® | plazomicin | Achaogen | complicated urinary tract infections (cUTI) including pyelonephritis | 2018/06/25 | 8:12.02 - Aminoglycosides | 1P | 210303 |
| Epidiolex® | cannabidiol | GW Research | seizures associated with Lennox-Gastaut or Dravet syndrome | 2018/06/25 | 28:12.92 - Anticonvulsants, Misc | 1P | 210365 |
| Braftovi® | encorafenib | Array Biopharma | unresectable or metastatic melanoma with a BRAF V600E or V600K mutation; in combination with binimetinib | 2018/06/27 | 10:00 - Antineoplastic Agents | 1/4S | 210496 |
| Mektovi® | binimetinib | Array Biopharma | unresectable or metastatic melanoma with a BRAF V600E or V600K mutation; in combination with encorafenib | 2018/06/27 | 10:00 - Antineoplastic Agents | 1/4S | 210498 |
| Qbrexza® | glycopyrronium tosylate | Dermira | primary axillary hyperhidrosis | 2018/06/28 | 84:92 - Skin and Mucous Membrane Agents, Misc; 12:08.08 - Antimuscarinics/Antispasmodics | 3S | 210361 |
| Iclevia® | ethinyl estradiol; levonorgestrel | Aurobindo | birth control | 2018/06/29 | 68:12 - Contraceptives | 206850 | |
| TPOXX® | tecovirimat | Siga | smallpox disease caused by variola virus | 2018/07/13 | 8:18.92 - Antivirals, Misc | 1P | 208627 |
| Symtuza® | darunavir; cobicistat; emtracitabine; tenofovir alafenamide | Janssen | HIV-1 infection | 2018/07/17 | 8:18.08.08; 92:92; 8:18.08.20; 8:18.08.20 | 4S | 210455 |
| Krintafel® | tafenoquine | GlaxoSmithKline | radical cure (prevention of relapse) of Plasmodium vivax malaria | 2018/07/20 | 8:30.08 - Antimalarials | 1P | 210795 |
| Tibsovo® | ivosidenib | Agios | relapsed or refractory acute myeloid leukemia (AML) | 2018/07/20 | 10:00 - Antineoplastic Agents | 1P | 211192 |
| Nivestym® | filgrastim-aafi | Hospira | febrile neutropenia | 2018/07/20 | 20:16 - Hematopoietic Agents | 761080 | |
| Orilissa® | elagolix | Abbvie | management of pain associated with endometriosis | 2018/07/23 | 68:18.04 - Antigonadotropins | 1P | 210450 |
| Omegaven® | fish oil triglycerides | Fresenius Kabi | source of calories and fatty acids in pediatric patients with parenteral nutrition-associated cholestasis (PNAC) | 2018/07/27 | 40:20 - Caloric Agents | 1P | 210589 |
| Azedra® | iobenguane I-131 | Progenics | pheochromocytoma or paraganglioma | 2018/07/31 | 10:00 - Antineoplastic Agents | 5P | 209607 |
| Mulpleta® | lusutrombopag | Shionogi | thrombocytopenia in adults with chronic liver disease | 2018/07/31 | 20:16 - Hematopoietic Agents | 1P | 210923 |
| Panzyga® | immune globulin intravenous, human-ifas | Octapharma | primary humoral immunodeficiency (PI); chronic immune thrombocytopenic purpura (ITP) | 2018/08/02 | 80:04 - Antitoxins and Immune Globulins | 125587 | |
| Poteligeo® | mogamulizumab-kpkc | Kyowa Kirin | relapsed or refractory mycosis fungoides or Sezary syndrome | 2018/08/08 | 10:00 - Antineoplastic Agents | 761051 | |
| Arakoda® | tafenoquine | 60 Degrees | prophylaxis of malaria | 2018/08/08 | 8:30.08 - Antimalarials | 5S | 210607 |
| Galafold® | migalastat | Amicus | Fabry disease | 2018/08/10 | 92:92 - Other Miscellaneous Therapeutic Agents | 1P | 208623 |
| Annovera® | segesterone; ethinyl estradiol | Population Council | combination hormonal contraceptive (CHC) | 2018/08/10 | 68:12 - Contraceptives | 1/4S | 209627 |
| Onpattro® | patisiran | Alnylam | polyneuropathy of hereditary transthyretin-mediated amyloidosis (hATTR) | 2018/08/10 | 92:92 - Other Miscellaneous Therapeutic Agents | 1P | 210922 |
| Cequa® | cyclosporine | Sun Pharma | keratoconjunctivitis sicca (dry eye) | 2018/08/14 | 52:08.92 - Anti-inflammatory Agents, Misc | 5S | 210913 |
| Diacomit® | stiripentol | Biocodex SA | seizures assoc with Dravet syndrome together with clobazam | 2018/08/20 | 28:12.92 - Anticonvulsants, Misc | 1P | 206709 |
| Inveltys® | loteprednol etabonate | Kala | post-operative inflammation and pain following ocular surgery | 2018/08/22 | 52:08.08 - Corticosteroids | 5 | 210565 |
| Oxervate® | cenegermin-bkbg | Dompé | neurotrophic keratitis | 2018/08/22 | 52:92 - EENT Drugs, Misc | 761094 | |
| Takhzyro® | lanadelumab-flyo | Dyax | hereditary angioedema | 2018/08/23 | 92:32 - Complement Inhibitors | 761090 | |
| Altreno® | tretinoin | Dow | acne vulgaris | 2018/08/23 | 84:16 - Cell Stimulants and Proliferants | 5 | 209353 |
| Xerava® | eravacycline | Tetraphase | complicated intra-abdominal infections except cUTI | 2018/08/27 | 8:12.24.08 - Fluorocyclines (new class) | 1P | 211109 |
| Jivi® | antihemophilic factor (recombinant), PEGylated-aucl (INN: damoctocog alfa pegol) | Bayer | bleeding management/prophylaxis with hemophilia A (congenital Factor VIII deficiency) | 2018/08/29 | 20:28.16 - Hemostatics | 125661 | |
| Pifeltro® | doravirine | Merck Sharp Dohme | HIV-1 infection | 2018/08/30 | 8:18.08.16 - HIV Nonnucleoside Reverse Transcriptase Inhibitors (NNRTIs) | 1S | 210806 |
| Delstrigo® | doravirine; lamivudine; tenofovir (TDF) | Merck Sharp Dohme | HIV-1 infection | 2018/08/30 | 8:18.08.16 - HIV Nonnucleoside Reverse Transcriptase Inhibitors (NNRTIs); 8:18.08.20; 8:18.08.20 | 4S | 210807 |
| Sympazan® | clobazam | Aquestive | seizures associated with Lennox-Gastaut Syndrome | 2018/08/31 | 28:12.08 - Benzodiazepines | 3S | 210833 |
| Tiglutik® | riluzole | Italfarmaco SPA | amyotrophic lateral sclerosis (ALS) | 2018/09/05 | 28:92 - Central Nervous System Agents, Misc | 3S | 209080 |
| Cassipa® | buprenorphine; naloxone | Teva | opioid dependence | 2018/09/07 | 28:08.12 - Opiate Partial Agonists; 28:10 - Opiate Antagonists | 5S | 208042 |
| Xelpros® | latanoprost | Sun | reduction of intraocular pressure in open-angle glaucoma or ocular hypertension | 2018/09/12 | 52:40.28 - Prostaglandin Analogs | 3S | 206185 |
| Lumoxiti® | moxetumomab pasudotox-tdfk | AstraZeneca | relapsed or refractory hairy cell leukemia (HCL) | 2018/09/13 | 10:00 - Antineoplastic Agents | 761104 | |
| Seizalam® | midazolam | Meridian | status epilepticus | 2018/09/14 | 28:12.08 - Benzodiazepines (Anticonvulsants); 28:24.08 - Benzodiazepines (Anxiolytics, Sedatives, and Hypnotics) | 10S | 209566 |
| Ajovy® | fremanezumab-vfrm | Teva | migraine headaches | 2018/09/14 | 28:32.92 - Antimigraine Agents, Misc | 761089 | |
| Copiktra® | duvelisib | Verastem | relapsed or refractory chronic lymphocytic leukemia (CLL), small lymphocytic lymphoma (SLL) or follicular lymphoma (FL) | 2018/09/24 | 10:00 - Antineoplastic Agents | 1P | 211155 |
| Vizimpro® | dacomitinib | Pfizer | first-line treatment of metastatic non-small cell lung cancer (NSCLC) with EGFR mutations | 2018/09/27 | 10:00 - Antineoplastic Agents | 1/4P | 211288 |
| Emgality® | galcanezumab-gnlm | Eli Lilly | migraine headaches | 2018/09/27 | 28:32.92 - Antimigraine Agents, Misc | 761063 | |
| Arikayce® | amikacin liposome inhalation | Insmed | refractory Mycobacterium avium complex (MAC) lung disease | 2018/09/28 | 8:12.02 - Aminoglycosides | 3P | 207356 |
| Xyosted® | testosterone enanthate | Antares | replacement therapy in males due to deficiency or absence of endogenous testosterone | 2018/09/28 | 68:08 - Androgens | 3S | 209863 |
| Libtayo® | cemiplimab-rwlc | Regeneron | metastatic cutaneous squamous cell carcinoma (CSCC) or locally advanced CSCC | 2018/09/28 | 10:00 - Antineoplastic Agents | 761097 | |
| Seysara® | sarecycline | Allergan | inflammatory lesions of non-nodular moderate to severe acne vulgaris | 2018/10/01 | 8:12.24 - Tetracyclines | 1S | 209521 |
| Nuzyra® | omadacycline | Paratek | community-acquired bacterial pneumonia (CABP); acute bacterial skin and skin structure infections (ABSSSI) | 2018/10/02 | 8:12.24.04 - Aminomethylcyclines (new class) | 1P | 209816, 209817 |
| Tegsedi® | inotersen | Ionis | polyneuropathy of hereditary transthyretin-mediated amyloidosis (hATTR) | 2018/10/05 | 92:18 - Antisense Oligonucleotides (ASO) | 1P | 211172 |
| Revcovi® | elapegademase-lvlr | Leadiant | adenosine deaminase severe combined immune deficiency (ADA-SCID) | 2018/10/05 | 44:00 - Enzymes | 761092 | |
| Yutiq™ | fluocinolone acetonide | Eyepoint | chronic non-infectious posterior segment uveitis | 2018/10/12 | 52:08.08 - Corticosteroids (EENT) | 5S | 210331 |
| Talzenna® | talazoparib | Pfizer | deleterious germline BRCA-mutated (gBRCAm) HER2-negative locally advanced or metastatic breast cancer | 2018/10/16 | 10:00 - Antineoplastic Agents | 1S | 211651 |
| Qmiiz® ODT | meloxicam | Tersera | osteoarthritis (OA), rheumatoid arthritis (RA), juvenile rheumatoid arthritis (JRA) | 2018/10/19 | 28:08.04.92 - Other Nonsteroidal Anti-inflammatory Agents | 3S | 211210 |
| Khapzory® | levoleucovorin | Spectrum | rescue after high-dose MTX therapy; folic acid antagonists overdosage; metastatic colorectal cancer in combo with fluorouracil | 2018/10/19 | 92:12 - Antidotes | 2S | 211226 |
| Xofluza® | baloxavir | Shionogi | acute uncomplicated influenza virus infection | 2018/10/24 | 8:18.92 - Antivirals, Misc | 1P | 210854 |
| Bijuva® | estradiol; progesterone | Therapeutics MD | moderate to severe vasomotor symptoms due to menopause | 2018/10/28 | 68:16.04 - Estrogens; 68:32 - Progestins | 4S | 210132 |
| Hyrimoz® | adalimumab-adaz | Sandoz | RA, JIA, PsA, AS, CD, UC, Ps | 2018/10/30 | 92:36 - Disease-modifying Antirheumatic Drugs; 92:20 - Immunomodulatory Agents; 56:92 - GI Drugs, Misc | 761071 | |
| Sympazan® | clobazam | Aquestive | seizures associated with Lennox-Gastaut Syndrome (LGS) | 2018/11/01 | 28:12.08 - Benzodiazepines | 3S | 210833 |
| Dsuvia® | sufentanil | AcelRx | acute severe pain | 2018/11/02 | 28:08.08 - Opiate Agonists | 3S | 209128 |
| Lorbrena® | lorlatinib | Pfizer | anaplastic lymphoma kinase (ALK)-positive metastatic non-small cell lung cancer (NSCLC) | 2018/11/02 | 10:00 - Antineoplastic Agents | 1P | 210868 |
| Udenyca® | pegfilgrastim-cbqv | Coherus | febrile neutropenia | 2018/11/02 | 20:16 - Hematopoietic Agents | 761039 | |
| Bryhali® (previously Jemdel) | halobetasol propionate | Dow | plaque psoriasis | 2018/11/06 | 84:06.08 - Corticosteroids | 3S | 209355 |
| Yupelri® | revefenacin | Theravance | maintenance of chronic obstructive pulmonary disease (COPD) | 2018/11/09 | 12:08.08 - Antimuscarinics/Antispasmodics | 1S | 210598 |
| Aemcolo® | rifamycin | Cosmo | travelers' diarrhea due to noninvasive E. coli | 2018/11/16 | 8:12.28.30 - Rifamycins | 1P | 210910 |
| Temixys® | lamivudine; tenofovir (TDF) | Celltrion | HIV-1 infection | 2018/11/16 | 8:18.08.20 - HIV Nucleoside and Nucleotide Reverse Transcriptase Inhibitors | 5S | 211284 |
| ReadyPrep CHG® | chlorhexidine gluconate | Medline | topical disinfectant | 2018/11/20 | 84:04.92 - Local Anti-infectives, Misc | 5S | 207964 |
| Gamifant® | emapalumab-lzsg | Novimmune | primary hemophagocytic lymphohistiocytosis (HLH) | 2018/11/20 | 92:44 - Immunosuppressive Agents | 761107 | |
| Daurismo® | glasdegib | Pfizer | acute myeloid leukemia (AML) | 2018/11/21 | 10:00 - Antineoplastic Agents | 1P | 210656 |
| Spy Agent Green® | indocyanine green | Novadaq | visualization of vessels (micro and macro vasculature), blood flow and tissue perfusion; extrahepatic biliary ducts; and lymph nodes and lymphatic vessels | 2018/11/21 | 36:68 - Roentgenographic and Other Imaging Agents | 5S | 211580 |
| Vitrakvi® | larotrectinib | Loxo | solid tumors with NTRK gene fusion | 2018/11/26 | 10:00 - Antineoplastic Agents | 1P | 210861, 211710 |
| Xospata® | gilteritinib | Astellas | relapsed or refractory acute myeloid leukemia (AML) with a FLT3 mutation | 2018/11/28 | 10:00 - Antineoplastic Agents | 1S | 211349 |
| Truxima® | rituximab-abbs | Celltrion | CD20-positive B-cell non-Hodgkin's lymphoma (NHL) | 2018/11/28 | 10:00 - Antineoplastic Agents | 761088 | |
| Firdapse® | amifampridine phosphate | Catalyst | Lambert-Eaton myasthenic syndrome (LEMS) in adults | 2018/11/28 | 92:92 - Other Miscellaneous Therapeutic Agents | 1O/P | 208078 |
| Dvorah® | acetaminophen; caffeine; dihydrocodeine | Larken | moderate to moderately severe pain | 2018/12/06 | 28:08.92 - Analgesics and Antipyretics, Misc; 28:20.32 - Respiratory and CNS Stimulants; 28:08.08 - Opiate Agonists | 204209 | |
| Tolsura® | itraconazole | Mayne | blastomycosis, histoplasmosis, aspergillosis | 2018/12/11 | 8:14 - Antifungals | 5S | 208901 |
| Cutaquig® | immune globulin subcutaneous, human-hipp | Octapharma | primary humoral immunodeficiency (PI) | 2018/12/12 | 80:04 - Antitoxins and Immune Globulins | 125668 | |
| Motegrity® | prucalopride | Shire | chronic idiopathic constipation (CIC) | 2018/12/14 | 56:32 - Prokinetic Agents | 1S | 210166 |
| Herzuma® | trastuzumab-pkrb | Celltrion | HER2-overexpressing breast cancer | 2018/12/14 | 10:00 - Antineoplastic Agents | 761091 | |
| Ezallor® | rosuvastatin | Sun | dyslipidemias | 2018/12/18 | 24:06.08 - HMG-CoA Reductase Inhibitors | 5S | 208647 |
| Licart® | diclofenac epolamine | Institut Biochimique | acute pain due to minor strains, sprains, and contusions | 2018/12/19 | 28:08.04.92 - Other Nonsteroidal Anti-inflammatory Agents | 3/4S | 206976 |
| Elepsia XR® | levetiracetam | Sun | partial-onset seizures | 2018/12/20 | 28:12.92 - Anticonvulsants, Miscellaneous | 5S | 204417 |
| Asparlas® | calaspargase pegol-mknl | Servier | acute lymphoblastic leukemia (ALL) | 2018/12/20 | 10:00 - Antineoplastic Agents | 761102 | |
| Ultomiris® | ravulizumab-cwvz | Alexion | paroxysmal nocturnal hemoglobinuria (PNH) | 2018/12/21 | 92:32 - Complement Inhibitors | 761108 | |
| Elzonris® | tagraxofusp-erzs | Stemline | blastic plasmacytoid dendritic cell neoplasm (BPDCN) | 2018/12/21 | 10:00 - Antineoplastic Agents | 761116 | |
| Inbrija® | levodopa | Acorda | off episodes in Parkinson's disease | 2018/12/21 | 28:36.16 - Dopamine Precursors | 3S | 209184 |
| Brixadi® | buprenorphine | Braeburn | moderate to severe pain | 2018/12/21 | 28:08.12 - Opiate Partial Agonists | 3P | 210136 |
| AHFS Class | Change Date | Change Description |
|---|---|---|
| 84:06.08 - Corticosteroids | 2017/12/15 | New subclass |
| 84:06.20 - Nonsteroidal Anti-inflammatory Agents | 2017/12/15 | New subclass |
| 84:06.92 - Anti-inflammatory Agents, Miscellaneous | 2017/12/15 | New subclass |
| 68:44 - Renin-Angiotensin-Aldosterone System (RAAS) | 2017/12/21 | New subclass |
| 40:92 - Electrolytic, Caloric, and Water Balance Agents; Misc | 2018/04/01 | New subclass |
| 8:12.24.08 - Fluorocyclines | 2018/08/27 | New subclass |
| 68:20.08.04 - Rapid-Acting Insulins | 2018/09/25 | New subclass |
| 68:20.08.08 - Short-Acting Insulins | 2018/09/25 | New subclass |
| 68:20.08.12 - Intermediate-Acting Insulins | 2018/09/25 | New subclass |
| 68:20.08.16 - Long-Acting Insulins | 2018/09/25 | New subclass |
| 8:12.24.04 - Aminomethylcyclines | 2018/10/03 | New subclass |
| 52:40.32 - Rho Kinase Inhibitors | 2018/11/05 | New subclass |
| 36:68 - Roentgenographic and Other Imaging Agents | 2018/11/05 | Name change |
| Drug Name(s) | Active Ingred | Change Date |
Old AHFS Class | New AHFS Class |
|---|---|---|---|---|
| Eucrisa® | crisaborole | 2017/12/15 | 84:06 - Anti-inflammatory Agents | 84:06.92 - Anti-inflammatory Agents, Miscellaneous |
| Aclovate® | alclometasone | 2017/12/15 | 84:06 - Anti-inflammatory Agents | 84:06.08 - Corticosteroids |
| Cyclocort® | amcinonide | 2017/12/15 | 84:06 - Anti-inflammatory Agents | 84:06.08 - Corticosteroids |
| Alphatrex®, Betatrex®, Beta-Val®, Diprolene®, Luxiq®, Maxivate® | betamethasone | 2017/12/15 | 84:06 - Anti-inflammatory Agents | 84:06.08 - Corticosteroids |
| Clobevate®, Clobex®, Cormax®, Embeline®, Olux®, Temovate® | clobetasol | 2017/12/15 | 84:06 - Anti-inflammatory Agents | 84:06.08 - Corticosteroids |
| Cloderm® | clocortolone | 2017/12/15 | 84:06 - Anti-inflammatory Agents | 84:06.08 - Corticosteroids |
| Desonate®, DesOwen®, Verdeso® | desonide | 2017/12/15 | 84:06 - Anti-inflammatory Agents | 84:06.08 - Corticosteroids |
| Topicort® | desoximetasone | 2017/12/15 | 84:06 - Anti-inflammatory Agents | 84:06.08 - Corticosteroids |
| Psorcon® | diflorasone | 2017/12/15 | 84:06 - Anti-inflammatory Agents | 84:06.08 - Corticosteroids |
| Capex®, Derma-Smoothe/FS®, Lidex®, Lidex-E®, Synalar®, Synemol® | fluocinolone/fluocinonide | 2017/12/15 | 84:06 - Anti-inflammatory Agents | 84:06.08 - Corticosteroids |
| Cordran® | flurandrenolide | 2017/12/15 | 84:06 - Anti-inflammatory Agents | 84:06.08 - Corticosteroids |
| Halog®, Halog-E® | halcinonide | 2017/12/15 | 84:06 - Anti-inflammatory Agents | 84:06.08 - Corticosteroids |
| Ultravate® | halobetasol | 2017/12/15 | 84:06 - Anti-inflammatory Agents | 84:06.08 - Corticosteroids |
| Ala-Cort®, Anucort-HC®, Anusert-HC®, Anusol-HC®, Cetacort®, Cortizone®, Dermacort®, Lanacort®, Proctocort®, Sarnol-HC®, Texacort®, Westcort® | hydrocortisone | 2017/12/15 | 84:06 - Anti-inflammatory Agents | 84:06.08 - Corticosteroids |
| Elocon® | mometasone | 2017/12/15 | 84:06 - Anti-inflammatory Agents | 84:06.08 - Corticosteroids |
| Dermatop® | prednicarbate | 2017/12/15 | 84:06 - Anti-inflammatory Agents | 84:06.08 - Corticosteroids |
| Aristocort®, Flutex®, Kenalog®, Triacet® | triamcinolone | 2017/12/15 | 84:06 - Anti-inflammatory Agents | 84:06.08 - Corticosteroids |
| Pennsaid®, Solaraze® 3% Gel, Voltaren® 1% Gel | diclofenac sodium | 2017/12/15 | 84:92 - Skin and Mucous Membrane Agents, Misc | 84:06.20 - Nonsteroidal Anti-inflammatory Agents |
| Inflectra®, Ixifi®, Remicade®, Renflexis® | infliximab, -abda, -dyyb, -qbtx | 2018/05/14 | 56:92, 92:20, 92:36 | 56:92, 84:92, 92:20, 92:36 |
| Simponi®, Simponi Aria® | golimumab | 2018/05/14 | 92:20, 92:36 | 56:92, 92:20, 92:36 |
| Otezla® | apremilast | 2018/05/14 | 84:92, 92:36 | 84:92, 92;20, 92:36 |
| Afrezza® | insulin human inhalation powder | 2018/09/25 | 68:20.08 - Insulins | 68:20.08.04 - Rapid-Acting Insulins |
| Fiasp®, NovoLOG®, NovoLOG® Mix 70/30 (combination), Ryzodeg® 70/30 (combination) | insulin aspart | 2018/09/25 | 68:20.08 - Insulins | 68:20.08.04 - Rapid-Acting Insulins |
| NovoLOG® Mix 70/30 (combination) | insulin aspart protamine | 2018/09/25 | 68:20.08 - Insulins | 68:20.08.12 - Intermediate-Acting Insulins |
| Apidra® | insulin glulisine | 2018/09/25 | 68:20.08 - Insulins | 68:20.08.04 - Rapid-Acting Insulins |
| AdmeLOG®, HumaLOG®, HumaLOG® Mix 75/25 (combination) | insulin lispro | 2018/09/25 | 68:20.08 - Insulins | 68:20.08.04 - Rapid-Acting Insulins |
| HumaLOG® Mix 75/25 (combination) | insulin lispro protamine | 2018/09/25 | 68:20.08 - Insulins | 68:20.08.12 - Intermediate-Acting Insulins |
| HumuLIN® N, HumuLIN® R, NovoLIN® N, NovoLIN® R, HumuLIN® 70/30 (combination), NovoLIN® 70/30 (combination) | insulin human | 2018/09/25 | 68:20.08 - Insulins | 68:20.08.08 - Short-Acting Insulins |
| HumuLIN® 70/30 (combination), NovoLIN® 70/30 (combination) | insulin human isophane (NPH) | 2018/09/25 | 68:20.08 - Insulins | 68:20.08.12 - Intermediate-Acting Insulins |
| Tresiba®, Ryzodeg® 70/30 (combination), Xultophy® 100/3.6 (combination) | insulin degludec | 2018/09/25 | 68:20.08 - Insulins | 68:20.08.16 - Long-Acting Insulins |
| Levemir® | insulin detemir | 2018/09/25 | 68:20.08 - Insulins | 68:20.08.16 - Long-Acting Insulins |
| Basaglar®, Lantus®, Lusduna®, Toujeo®, Soliqua® 100/33 (combination) | insulin glargine | 2018/09/25 | 68:20.08 - Insulins | 68:20.08.16 - Long-Acting Insulins |
| Rhopressa® | netarsudil | 2018/11/05 | 52:40.92 - Antiglaucoma Agents, Misc | 52:40.32 - Rho Kinase Inhibitors |
| Gleolan® | aminolevulinic acid oral solution | 2018/11/05 | 36:68 - Roentgenographic and Other Imaging Agents |